Shared Receptor Mechanisms of βc Family Cytokines and Their Roles in Hematopoietic and Immune Regulation
GM-CSF, IL-3, and IL-5 integrate hematopoietic and immune signals through the shared βc chain, respectively regulating myeloid cells, basophils, and eosinophils, and participating in hematologic malignancies, allergy, and autoimmune inflammation.
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