Roles of the CEACAM Family in Tumor Progression, Immune Regulation, and Antibody-Drug Conjugate Development
The CEACAM family participates in epithelial homeostasis through cell adhesion, receptor signaling, and immune regulation. CEACAM5 and CEACAM6 are aberrantly overexpressed in multiple solid tumors and provide important targets for tumor biomarkers, antibody-drug conjugates, and cellular ...
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