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Copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC)

The azide-alkyne Huisgen cycloaddition is a 1,3-dipolar cycloaddition that involves the reaction between an azide and a terminal or internal alkyne, leading to the formation of a 1,2,3-triazole. Rolf Huisgen was a trailblazer in understanding the wide applicability of this organic reaction.

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