drug-delivery formulations

Mechanisms of Action, Formulation Screening, and Safety Evaluation of Solubilizers, Hydrotropes, and Cosolvents in Drug-Delivery Systems

Poorly soluble drugs in aqueous drug-delivery systems are prone to insufficient drug-loading concentrations, crystallization during storage, and precipitation after dilution with physiological fluids. Solubilizers, hydrotropes, and cosolvents can increase drug solubility through micellar ...