生长激素(Growth Hormone)的分泌调控、GHR信号与GH–IGF-1轴
生长激素(Growth ...
用于检测、定量和定位抗原与抗体的技术——ELISA、免疫印迹、免疫组化与流式细胞术。以下是我们知识库中标注该主题的实验方案、常见问题与技术文章。
生长激素(Growth ...
Growth Hormone (GH) is an important peptide hormone secreted by the anterior pituitary. Through GHR–JAK2–STAT5 signaling and the GH–IGF-1 axis, it regulates linear growth, skeletal and muscle development, lipid mobilization, and glucose metabolism. GH research requires simultaneous consideration ...
Aging involves persistent dysregulation of nutrient sensing, energy metabolism, protein homeostasis, and chronic inflammation. IIS, mTOR, AMPK, NF-κB, and Sirtuins are interconnected through nodes including AKT, FOXO, ULK1, and NAD⁺ and jointly regulate cell growth, autophagy, stress adaptation, ...
衰老涉及营养感知、能量代谢、蛋白质稳态和慢性炎症的持续失衡。IIS、mTOR、AMPK、NF-κB和Sirtuins通过AKT、FOXO、ULK1及NAD⁺等节点相互连接,共同调控细胞生长、自噬、应激适应和衰老相关分泌表型。
常与免疫学实验一起研究的技术。