(S)-(+)-2-Aminooctane: Handling & Application Protocol
Step-by-step protocol for handling, storing, and using (S)-(+)-2-Aminooctane (S657055) in asymmetric synthesis and chiral resolution workflows.
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Primary Amines
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Why Primary and Secondary Amines Have Difficulty Participating Directly in the Classical Mitsunobu Reaction: Mechanism, Inversion of Configuration, and Reaction Scope of BEHT-Mediated Alcohol Amination
The classical Mitsunobu reaction can activate alcohols under relatively mild conditions and form new C—N, C—O, or C—S bonds through nucleophilic substitution. With suitable chiral secondary alcohols, the reaction is generally accompanied by inversion of configuration. It is therefore widely used ...
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