Emerging Fat-Loss Target: The INHBE/Activin E–ALK7 Signaling Axis
Activin E encoded by INHBE is mainly produced by the liver and regulates lipid storage and lipolysis through ALK7/ACVR1C in adipocytes. Reducing INHBE or ALK7 signaling can promote fat mobilization and alter fat distribution, making this liver–adipose tissue endocrine axis an emerging fat-loss ...
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