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lignans

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Structure–Property Relationships of Oxygen-Containing Functional Groups in Lignans: Hydrogen Bonding, Polarity, Electronic Effects, Side-Chain Oxidation, and Glycosylation

Oxygen in lignan molecules can occur in different functional groups, including phenolic hydroxyls, aryl methyl ethers, methylenedioxy groups, aliphatic alcohols, carbonyl groups, lactones, and glycosides. When the functional state of an oxygen atom changes, the manner in which its lone pairs ...

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Central Chirality, Axial Chirality, and Conformational Dynamics of Lignans

Once the two-dimensional connectivity of lignans is established, their three-dimensional structures can still differ substantially as a result of tetrahedral stereocenters, restricted biaryl rotation, and changes in ring conformation. Whether a tetrahedral carbon constitutes a stereocenter ...

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