Translatome Remodeling during Fasting and Ketogenic Diets and Metabolic Vulnerabilities in Pancreatic Cancer
Both fasting and ketogenic diets can enhance fatty acid utilization and ketone body production. AMPK–MNK–eIF4E signaling and 5′UTR-dependent selective translation participate in this nutritional adaptation and influence the ability of pancreatic cancer to adapt to a ketogenic metabolic ...
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