From Serotonin to Triptans: Recognition of the Indole–Ethylamine Pharmacophore, C5 Substitution, and 5 HT₁B/5 HT₂B Selectivity
Serotonin (5-hydroxytryptamine, 5 HT) has a typical tryptamine structure: an ethylamine side chain is attached at the C3 position of the indole ring, and a hydroxyl group is present at C5. The antimigraine drug sumatriptan retains this indole–ethylamine scaffold while extending the C5 position ...
危险品化学品经营许可证（带存储）