in vivo metabolic tracing

Applications of Stable Isotope-Labeled Compounds in In Vivo Metabolic Studies

Stable isotope-labeled compounds use ²H, ¹³C, ¹⁵N, or ¹⁸O to label metabolic substrates, allowing their transformation and fate in vivo to be identified by mass spectrometry or nuclear magnetic resonance. This technology can be used to determine substrate sources, metabolic pathways, interorgan ...