Recombinant Human GNPTAB Protein: Function & Research
Explore the biology, function, and research applications of Recombinant Human GNPTAB Protein for lysosomal disease and enzyme trafficking studies.
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Explore the biology, function, and research applications of Recombinant Human GNPTAB Protein for lysosomal disease and enzyme trafficking studies.
探索重组人GNPTAB蛋白的生物学特性、功能及其在溶酶体疾病与酶转运研究中的应用。
LYSET是维持溶酶体酶正确运输的重要高尔基体膜蛋白,可通过调控GNPT和甘露糖-6-磷酸通路维持溶酶体降解能力。部分肿瘤细胞在营养匮乏环境中依赖溶酶体分解胞外蛋白获取氨基酸,使LYSET成为连接溶酶体功能与癌细胞代谢适应的重要研究靶点。 ...
LYSET is an important Golgi membrane protein that maintains the correct trafficking of lysosomal enzymes by regulating GNPT and the mannose-6-phosphate pathway. Under nutrient-limited conditions, some cancer cells depend on lysosomal degradation of extracellular proteins to obtain amino acids, ...
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