Whether chemical reagents will deteriorate during storage depends on two factors: internal factors, which are determined by the chemical structure of the reagent itself, and external factors, which are determined by the environmental conditions in which the reagent is stored.
In the process of developing new drugs, chiral dihydroazaindolecarboxylic acid (R)-1 is in great demand as a key starting material for the synthesis of active pharmaceutical ingredients (APIs). However, the traditional synthesis method, chiral supercritical fluid chromatographic separation, is ...