主题

drug target ligand

用于检测、定量和定位抗原与抗体的技术——ELISA、免疫印迹、免疫组化与流式细胞术。以下是我们知识库中标注该主题的实验方案、常见问题与技术文章。

3 项资源 · 实验方案、常见问题与文章
article

GDC-1971: SHP2 Inhibitor Ushering in a New Era of Cancer Treatment

In recent years, protein tyrosine phosphatase SHP2 has become a highly regarded research target in the field of oncology in mediating the RAS-driven MAPK signaling pathway. Its treatment methods are not limited to single drug use, but also can work together with KRAS inhibitors, showing good ...

更新于 2024年3月阅读12分钟
article

Explore the Industrialization Process of SOS1 Inhibitor MRTX0902

MRTX0902 is a highly effective SOS1:KRAS complex inhibitor that exhibits excellent brain penetration, high oral bioavailability, and strong selectivity. When combined with MRTX849 (1,2)-adagrasib (KRAZATI), it can significantly enhance its anti-tumor activity.

更新于 2024年2月阅读12分钟
article

D-DTTA Salts of Azaindole Chiral Amines: New Options for Chemical Splitting

In the process of developing new drugs, chiral dihydroazaindolecarboxylic acid (R)-1 is in great demand as a key starting material for the synthesis of active pharmaceutical ingredients (APIs). However, the traditional synthesis method, chiral supercritical fluid chromatographic separation, is ...

更新于 2024年2月阅读12分钟

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常与免疫学实验一起研究的技术。