The detection of cell surface proteins mainly targets antigens on the cell membrane. Antibodies can directly bind to antigens on the cell surface, so fixation and permeabilization treatment are usually not required. The experimental operation is relatively simple, and the main focus is on the ...
The term "IDG families" likely refers to the Illuminating the Druggable Genome (IDG) project, which is a part of the broader NIH Common Fund's effort to explore and better understand the human genome, specifically focusing on the "druggable" portion of the genome.