Neurons have highly polarized structures, with axons and dendrites extending far from the soma. Synaptic activity, action potential conduction, Ca²⁺ buffering, and local protein homeostasis all depend on continuous mitochondrial energy supply. Directed mitochondrial transport, local docking, ...
Neuroinflammation is an inflammatory response formed in the nervous system under conditions such as infection, injury, metabolic stress, abnormal protein deposition, or immune imbalance. Its core lies in the dynamic imbalance among microglia, astrocytes, peripheral immune cells, the blood-brain ...
Apolipoproteins (Apos) are important protein components of lipoprotein particles. They participate in the transport of triglycerides, cholesterol, phospholipids, and lipid-soluble molecules, and determine the interactions between lipoproteins and receptors, enzymes, and transport proteins.
α-Synuclein is a small molecule protein mainly found in the presynaptic terminals of the central nervous system. It consists of 140 amino acids and has a molecular weight of about 19 kDa.