Differences in cytotoxicity evaluation arise first from differences in the biological process being measured. The Neutral Red assay primarily reflects cellular uptake of the dye and lysosomal retention capacity, whereas the MTT assay and the CCK-8 assay mainly reflect dehydrogenase-related ...
MTT colorimetry is a detection method based on cell metabolic activity. It is widely used in cell biology and pharmacology research to evaluate cell proliferation, cell activity, cytotoxicity, and drug screening.