In Alzheimer’s disease models, cholinergic detection should not focus only on measuring acetylcholine or acetylcholinesterase separately. The key is to assess the relationship among neurotransmitter levels, enzyme activity changes, cholinergic neuronal injury, and inflammatory responses. When ...
γ-Secretase is a multi-subunit enzyme complex that catalyzes the cleavage of various transmembrane proteins, including amyloid precursor protein (APP) and Notch. Processing of APP by γ-secretase leads to the production of amyloid-β peptides, which aggregate to form the amyloid plaques that are a ...
危险品化学品经营许可证（带存储）