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Pyruvate is a key metabolic node at the end of glycolysis. Depending on redox status, oxygen availability, cell type, and metabolic demand, pyruvate can enter different metabolic branches. PDC, LDH, and PDH respectively represent three typical routes from pyruvate toward ethanol fermentation, ...
丙酮酸是糖酵解末端的关键代谢节点，可根据氧化还原状态、氧供应、细胞类型和代谢需求进入不同分支。PDC、LDH与PDH分别代表丙酮酸向乙醇发酵、乳酸生成和氧化代谢转化的三类典型路径，三者的核心差异在于碳流去向、NADH再氧化方式、能量收益和代谢调控意义。 ...
Lactate dehydrogenase (LDH, EC 1.1.1.27) is a key redox enzyme catalyzing the terminal, reversible “lactate–pyruvate” step of glycolysis, using NAD⁺/NADH as coenzyme. It is widely distributed in multiple tissues, including myocardium, liver, skeletal muscle, kidney, and red blood cells.
乳酸脱氢酶（Lactate Dehydrogenase，LDH，EC 1.1.1.27）是糖酵解末端“乳酸–丙酮酸”可逆转化的关键氧化还原酶，依赖NAD⁺/NADH作为辅酶，广泛存在于心肌、肝脏、骨骼肌、肾脏、红细胞等多种组织。
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