Glucuronidation is an important phase II metabolic pathway in the clearance of drugs and endogenous metabolites, but its biological consequences do not necessarily terminate once the host conjugation reaction is completed.
Glycoprotein hormones consist of heterodimeric protein scaffolds and glycosylation modifications. The shared α-subunit provides folding, assembly, and secretion support, while the specific β-subunit determines receptor selectivity and principal biological effects. N-linked glycan site occupancy, ...
Fluconazole is a triazole antifungal agent (commonly categorized within the azole antifungal class) with the molecular formula C13H12F2N6O, molecular weight 306.271, and CAS No. 86386-73-4.