Interleukins

Interleukin Receptor Signaling: Mechanistic Analysis of the JAK-STAT and NF-κB Axes with an Overview of Assays, Experimental Models, and Translational Boundaries

Interleukins constitute a key group of cytokines produced by immune cells as well as multiple tissue-resident cell types. Their biological effects depend on the assembly of specific receptor complexes and the magnitude of downstream signal transduction, which in turn shapes immune-cell ...