Induced pluripotent stem cells (iPSCs) have self-renewal and multilineage differentiation capacities and can be used in disease modeling, drug screening, organoid construction, and cell therapy research. Directed differentiation of iPSCs depends on stage-specific signal regulation. Activin A, ...
Within the soluble cytokine network, colony-stimulating factors (CSFs) are a group of protein factors whose defining feature is the ability to drive proliferation and differentiation of hematopoietic progenitors and to regulate the production and functional maturation of myeloid cells.