Nerve Growth Factor: Molecular Features, Signaling Mechanisms, and Key Technical Application Points
Nerve growth factor (NGF) is a prototypical member of the neurotrophin family. Through interactions with the high-affinity receptor TrkA (NTRK1) and the low-affinity receptor p75NTR (NGFR), NGF regulates neuronal survival, axonal growth, synaptic plasticity, and processes related to injury repair.
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