Organoids can self-organize from tissue stem cells, primary cells, or pluripotent stem cells in a three-dimensional environment and partially reconstruct the cellular composition, spatial architecture, and functional characteristics of organs. They provide models that more closely resemble in ...
The lack of suitable in vitro models that accurately represent specific tissues and disease states is a major obstacle to basic and translational research. This has led to the development of 3D organoids, which provide greater complexity than 2D models and build stable, physiologically relevant ...
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