谷胱甘肽还原酶:维持GSH/GSSG稳态的黄素依赖还原体系及其检测与应用
谷胱甘肽还原酶(glutathione reductase,GR)是一类典型的黄素依赖型氧化还原酶,催化氧化型谷胱甘肽(GSSG)在NADPH供氢条件下还原为还原型谷胱甘肽(GSH),从而维持细胞内GSH/GSSG氧化还原缓冲体系的稳态。
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谷胱甘肽还原酶(glutathione reductase,GR)是一类典型的黄素依赖型氧化还原酶,催化氧化型谷胱甘肽(GSSG)在NADPH供氢条件下还原为还原型谷胱甘肽(GSH),从而维持细胞内GSH/GSSG氧化还原缓冲体系的稳态。
Glutathione reductase (GR) is a canonical flavin-dependent oxidoreductase that catalyzes the reduction of oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as the electron donor, thereby maintaining the steady state of the intracellular GSH/GSSG redox-buffering system.
Glutathione (GSH) is one of the most important low-molecular-weight thiols in cells. It participates in reactive oxygen species (ROS) detoxification, maintains protein thiols in a reduced state, drives the glutathione peroxidase/reductase cycle, and—together with oxidized glutathione ...
谷胱甘肽(glutathione, ...
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