Glutathione Reductase: A Flavin-Dependent Reductive System Maintaining GSH/GSSG Homeostasis, with Assays and Applications
Glutathione reductase (GR) is a canonical flavin-dependent oxidoreductase that catalyzes the reduction of oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as the electron donor, thereby maintaining the steady state of the intracellular GSH/GSSG redox-buffering system.
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