From Analytical Instrument to Synthetic Platform: A New Strategy for Reconstructing Automated Flow Solid-Phase Peptide Synthesis with Standard Analytical HPLC
Peptide synthesis is not a new problem. Since Merrifield established solid-phase peptide synthesis, resin supports, protecting-group strategies, coupling reagents, and heating methods have continued to evolve, with the same fundamental goals: improving chain-extension efficiency, reducing side ...
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