article mtDNA Stress and cGAS–STING/AIM2 Innate Immune Activation Mediated by CRAT Deficiency Intracellular DNA sensing is not always triggered directly by exogenous pathogens. In many noninfectious stress settings, its upstream origin is first a disruption of mitochondrial metabolic homeostasis. 更新于 2026年4月阅读12分钟
article CRAT缺失介导的mtDNA应激及cGAS–STING/AIM2先天免疫激活 细胞内DNA感知并非总由外源病原直接触发,在不少非感染性应激背景下,其上游首先是线粒体代谢稳态破坏。 更新于 2026年4月阅读12分钟