Ubiquitination is a highly complex type of post-translational modification. Through the coordinated action of ubiquitin molecules, ubiquitin chain structures, the E1-E2-E3 enzymatic cascade, and deubiquitinating enzymes, this system regulates substrate protein stability, subcellular ...
The study of carbohydrate-metabolic enzymes has expanded beyond their classical catalytic roles to include higher-order cellular programs such as replication progression, DNA damage repair, and inflammatory activation. Multiple carbohydrate-metabolic enzymes can acquire moonlighting functions ...