Depression involves multilevel abnormalities in monoaminergic transmission, the balance between glutamate and GABA, regulation of the stress axis, and synaptic plasticity. Different targets separately influence mood, reward, cognition, sleep, and stress responses and together form an ...
Norepinephrine is a core molecule that appears across neuroscience, pharmacology, and critical care medicine. In the periphery, it serves as an important chemical signal in the sympathetic nervous system and participates in the maintenance of vascular tone and perfusion pressure. In the central ...
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