常见问题(FAQs)

What are the limitations of the Foucault acylation reaction?

What are the limitations of the Foucault acylation reaction?

Although some limitations of related alkylation reactions (such as carbocation rearrangement and polyalkylation) have been overcome, there are some drawbacks to the Fourier acylation reaction.

① The acylation reaction produces only ketones. This is because formyl chloride decomposes into CO and HCl when exposed to these conditions.

② If the reactivity of aromatic compounds is lower than that of monohalobenzenes, they cannot participate in the reaction.

③ Aromatic amines cannot be used in this reaction because they form highly reactive complexes with Lewis acid catalysts.

目录: 常见问题(FAQs)
探索主题: Friedel–Crafts Acylation

Da — 若无特别说明,分子量单位默认为道尔顿。   Mw — 重均分子量。   Mn — 数均分子量。

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阿拉丁科学.《What are the limitations of the Foucault acylation reaction?》. 阿拉丁知识库,更新于 2023年7月25日。 https://www.aladdin-e.com/zh_cn/faqs/what-are-the-limitations-of-the-foucault-acylation-reaction-en.html
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