计算溶液所需的质量、体积或浓度。
,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
GNF-2-deg is a PROTAC degrader for dengue virus envelope protein ( DENV E protein ) with DC 50 of 0.83 μM. GNF-2-deg prevents viral entry by inhibiting E-mediated membrane fusion, prevents virion production by protein degradation, and thereby exhibits antiviral activity against DENV 2 with EC 90 of 3.5 μM. GNF-2-deg exhibits antiviral activity against ZIKV, JEV, WNV and YFV with EC 90 of 1.96-7.79 μM. (Pink: ligand for target protein ; Black: linker ; Blue: ligand for E3 ligase )