GHP-88309 is a broad-spectrum, orally active antiviral agent targeting paramyxoviruses , that targets the viral polymerase , interupts the viral RNA synthesis, and inhibits respiratory syncytial virus ( RSV ), measles virus ( MeV ), and canine distemper virus ( CDV ) with EC 50 of 0.06-1.2 μM. GHP-88309 exhibits anti-infectious efficacy in mouse models.