GSTP1-1 inhibitor 2 (Compound 5g) is an hGSTP1-1 ( glutathione S-transferase P1-1) inhibitor with an IC 50 value of 12.2 μM. GSTP1-1 inhibitor 2 exhibits significant cytotoxicity against DU-145, PC3, and MCF-7 cell lines, with CC 50 values of 36.6 μM, 11.9 μM, and 17.4 μM, respectively. It can be used in cancer research.