Geissoschizoline ((+)-Geissoschizoline) is a potent inhibitor of human AChE/BChE , with IC 50 s of 20.40 µM and 10.21 µM, respectively. Geissoschizoline emerges as a possible multi-target prototype that can be very useful in studies of preventing neurodegeneration and restoring neurotransmission. Geissoschizoline aiso is a potent anti-inflammatory agent.