计算溶液所需的质量、体积或浓度。
有货
为什么选择此级别
Moligand™ 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
-80℃储存。特低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 21 篇同行评审文献引用。
概述
Gastrodin, a phenolic glucoside, is the main active ingredient of the traditional Chinese medicinal compound Tianma. Gastrodin is an active component of Gastrodia elata Blume, a herb belonging to the Orchidaceae family.Gastrodin has been used as a control to estimate the gastrodin content in the leaves, roots and stems of Anoectochilus formosanus Hayata.
Information
Gastrodin (Gastrodine), an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases.
In vitro
Gastrodin is the most important and effective ingredient extracted from Chinese natural herbal Gastrodia elata. Gastrodin (30, 40, and 60 mM) significantly attenuates levels of neurotoxic proinflammatory mediators and proinflammatory cytokines by inhibition of the NF-kappaB signaling pathway and phosphorylation of MAPKs in LPS-stimulated microglial cells. However, It also upregulates the phosphatidylinositol 3-kinase (PI3-K)/Akt signaling, resulting in the inhibitory effects NF-kappaB and MAPKs activation in H9c2 cardiomyocytes.
In vivo
Gastrodin at 5 mg/kg can improve cycloheximide- and apomorphine-induced amnesia, but not scopolamine-induced acquisition impairment in rats. Thus, GAS can facilitate memory consolidation and retrieval, but not acquisition. LD50: Mice >1000mg/kg (i.v.)
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:≥99%
规格
英文别名
Gastrodine | β-D-Glucopyranoside, 4-(hydroxymethyl)phenyl
规格或纯度
Moligand™,10mM in DMSO
英文名称
Gastrodin
生化机理
天麻素是从中药天麻中提取的一种抗炎多酚，对神经退行性疾病有益。
储存条件
-80℃储存
运输条件
特低温运输
作用类型
抑制剂
名称和识别符
EC号
683-202-7
分子类型
小分子
Isomeric SMILES
C1=CC(=CC=C1CO)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
分子量
286.28
Reaxy-Rn
25441801
Reaxys-RN link address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25441801&ln=
技术文档
高级数据
化学和物理性质
比旋光度
-66.0 to -70.0 deg(C=1,H2O)
熔点
154-155°C
安全和危险性（GHS）
信号词
警告
危险声明
H302: 吞食有害
Merck Index
4375
质检证书（CoA,COO,BSE/TSE 和分析图谱)
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此产品的引用文献
溶液计算器
产品仅提供给经过验证的企业、机构和合格的专业人员用于研发。不适用于人类、动物、诊断或治疗。
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