计算溶液所需的质量、体积或浓度。
概述
Description
Gold nanoparticles (AuNPs) ranging from 2-200nm in diameter find applications in diverse fields.They show excellent biocompatibility and attractive physicochemical properties. AuNPs, as aggregates, is shown to be highly sensitive colloidal biosensors. Poly (ethylene) glycol (PEG) surface coating on gold nanoparticles helps in the reduction of protein adsorption, reduces nonspecific interactions with cells and greatly improves the pharmokinetics of these nanoparticles and disables aggregation of the nanoparticles. AuNPs coated with PEG 5000 exhibited highest colloidal stability. The methyl group, being hydrophobic acts as a protecting shield between the gold nanoparticles and the hydrophilic outer PEG coating and also leads to a further reduction of protein adsorption and macrophage uptake by the AuNPs.Several other specific applications have been listed below:Since they adhere to cell membranes, AuNPs may find use in cellular and intracellular targeting in targeted drug delivery applications and may also be used in biodistribution studies.AuNPs may also be used in photothermal therapy and radiotherapy.AuNPs ranging from 10 to 250 nm, were studied to have been absorbed primarily by liver and spleen , when injected intravenously in rats.Whereas, 10 nm nanoparticles were distributed more broadly into various organs.Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.
Description
Gold nanoparticles (AuNPs) ranging from 2-200nm in diameter find applications in diverse fields.They show excellent biocompatibility and attractive physicochemical properties. AuNPs, as aggregates, is shown to be highly sensitive colloidal biosensors. Poly (ethylene) glycol (PEG) surface coating on gold nanoparticles helps in the reduction of protein adsorption, reduces nonspecific interactions with cells and greatly improves the pharmokinetics of these nanoparticles and disables aggregation of the nanoparticles. AuNPs coated with PEG 5000 exhibited highest colloidal stability. The methyl group, being hydrophobic acts as a protecting shield between the gold nanoparticles and the hydrophilic outer PEG coating and also leads to a further reduction of protein adsorption and macrophage uptake by the AuNPs.Several other specific applications have been listed below:Since they adhere to cell membranes, AuNPs may find use in cellular and intracellular targeting in targeted drug delivery applications and may also be used in biodistribution studies.AuNPs may also be used in photothermal therapy and radiotherapy.AuNPs ranging from 10 to 250 nm, were studied to have been absorbed primarily by liver and spleen , when injected intravenously in rats.Whereas, 10 nm nanoparticles were distributed more broadly into various organs.Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.
规格
英文别名
Au NP OMe, Gold nanoparticles OMe terminated, Gold Colloid
规格或纯度
直径10 nm,甲基封端,PEG 5000涂层,外径50,在H₂O中分散
英文名称
Gold nanoparticles
储存条件
2-8°C储存
运输条件
低温运输
名称和识别符
分子类型
小分子
高级数据
化学和物理性质
溶解性
水：混溶
密度
1.00g/cm³
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溶液计算器
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