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金纳米粒子PEG 5000生物素终止
应用
直径为80 nm的金纳米颗粒(生物素封端,PEG 5000包被,OD 50,在H2O中分散)可用作治疗诊断剂,有望用于癌症治疗和COVID-19的治疗。它也可以用于生物传感应用中的病原体检测。AuNPs可用于制备SARS-CoV-2偶联物,用于通过侧向流免疫分析(lateral flow immunoassay)技术进行COVID-19检测。生物素官能化的金纳米颗粒适合于链霉亲和素标记的偶合物的结合。通过测量结合后样品吸光度的增加,金纳米颗粒标记可实现对链霉亲和素的直接检测。最大吸光度取决于金纳米颗粒的大小,其范围从5nm颗粒的515-520nm到100nm颗粒的572nm。
Gold nanoparticles PEG 5000 biotin terminatedBiotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent and ranges from 515-520nm for a 5nm particle to 572nm for a 100nm particle.Gold nanoparticles 80 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.