GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5 , cdk2 , and GSK-3 extracted from patent WO2002010141A1, example 9a. GSK-3/CDK5/CDK2-IN-1 can be used for the research of cancer , and neurodegenerative diseases
In Vitro
GSK-3/CDK5/CDK2-IN-1 inhibits the phosphorylation of cdk5 peptide substrate phosphorylation, with an IC 50 of less than about 50 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.