计算溶液所需的质量、体积或浓度。
,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
HVH-2930 is an inhibitor for heat shock protein 90 ( HSP90 ). HVH-2930 inhibits cell viability of BT474 (Trastuzumab sensitive) and JIMT-1 (Trastuzumab resistant), with IC 50 of 6.86 μM and 4.42 μM, through downregulation of HSP90 clients HER2, p-HER2, AKT , p-AKT, cyclin D1 and survivin. HVH-2930 exhibits antitumor efficacy in mouse models. HVH-2930 exhibits good pharmacokinetic characteristics in mice.