HDAC6-IN-47 (Compound S-29b) is inhibitor for HDAC , which exhibits high affinities to HDAC1 , HDAC2 , HDAC3 , HDAC6 , HDAC8 , HDAC10 with K i of 60, 56, 162, 0.44, 362 and 849 nM, respectively. HDAC6-IN-47 causes tubulin hyperacetylation in MV4-11, inhibits the proliferation of MV4-11 with an EC 50 of 0.50 µM. HDAC6-IN-47 can be used in research of leukemia.