计算溶液所需的质量、体积或浓度。
HDAC-IN-76 (compound 6i) is a histone deacetylase ( HDAC ) inhibitor. HDAC-IN-76 IC 50 values of 30 nM and 98 nM for Pf3D7 (chloroquine drug-susceptible strain) and PfDd2 (chloroquine drug-resistant strain), has a highly potent antimalarial activity against asexual blood-stage Plasmodium , respectively, and exhibits selective inhibition against parasites, with IC 50 values of 7 nM and 9 nM for human HDAC1 and HDAC6 , respectively, while inhibiting PfHDAC1.