计算溶液所需的质量、体积或浓度。
HDAC6-IN-5 (compound 11b) is a potent and BBB-penetrated HDAC6 inhibitor, with an IC 50 of 0.025 μM. HDAC6-IN-5 exhibits strong inhibitory activity against Aβ 1-42 self-aggregation and AChE , with IC 50 values of 3.0 and 0.72 μM. HDAC6-IN-5 can enhance neurite outgrowth without significant neurotoxicity.