3-Hydroxy Midostaurin-d 5 is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 ( FLT3 ) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively.