HV1-IN-1 hydrochloride is an inhibitor of the human voltage-gated proton channel ( hHV1 ). HV1-IN-1 hydrochlorideworks by binding to the VSD of the HV1 channel. The VSD is a component of the HV1 channel that is responsible for detecting changes in membrane potential and triggering the opening of the channel. HV1-IN-1 hydrochloride can be used in the study of cancer , neuroinflammation and immune response.