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| 活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
|---|
骆驼蓬灵
有货
库存信息
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| H423148-1ml |
1ml |
现货  |
|
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基本描述
| 别名 | 哈梅灵 | 3,4-二氢-7-甲氧基-1-甲基-β-咔晽 | 3,4-二氢-7-甲氧基-1-甲基-9H-吡啶并[3,4-b]吲哚 |
|---|---|
| 英文别名 | 3,4-Dihydro-7-methoxy-1-methyl-9-pyrido(3,4-b)indole | ACon1_000019 | DB13875 | KBio1_000950 | KBio2_000781 | LS-14204 | BRN 0207310 | KBio3_001759 | Spectrum5_001452 | BSPBio_002539 | KBio2_005917 | SCHEMBL3862598 | Armalin | 7-METHOXY-1-METHYL-4,9-DIHYD |
| 规格或纯度 | 10mM in DMSO |
| 英文名称 | Harmaline |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
关联靶点（人）
MAOA
Tclin
胺氧化酶[含黄素]A(Amine oxidase [flavin-containing] A)
(1 活性数据)
HTR1A
Tclin
Serotonin 1a (5-HT1a) receptor
(14969 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
TSHR
Tclin
Thyroid stimulating hormone receptor
(29986 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAOA
Tclin
Monoamine oxidase A
(11911 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ACHE
Tclin
Acetylcholinesterase
(18204 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAOB
Tclin
Monoamine oxidase B
(8835 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR1D
Tclin
Serotonin 1d (5-HT1d) receptor
(2897 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR1B
Tclin
Serotonin 1b (5-HT1b) receptor
(2801 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR2A
Tclin
Serotonin 2a (5-HT2a) receptor
(14758 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR2C
Tclin
Serotonin 2c (5-HT2c) receptor
(11471 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR3A
Tclin
Serotonin 3a (5-HT3a) receptor
(3366 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAPK11
Tchem
MAP kinase p38 beta
(2785 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
LCK
Tclin
Tyrosine-protein kinase LCK
(9212 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAPK14
Tchem
MAP kinase p38 alpha
(12866 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
GSK3B
Tclin
Glycogen synthase kinase-3 beta
(11785 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
POLB
Tchem
DNA polymerase beta
(23632 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PRKCZ
Tchem
Protein kinase C zeta
(2414 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MYLK
Tchem
Myosin light chain kinase, smooth muscle
(1267 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
STK3
Tchem
Serine/threonine-protein kinase MST2
(3069 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CSNK1D
Tchem
Casein kinase I delta
(4546 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SRC
Tclin
Tyrosine-protein kinase SRC
(10310 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CHEK2
Tchem
Serine/threonine-protein kinase Chk2
(4015 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PDPK1
Tchem
3-phosphoinositide dependent protein kinase-1
(3758 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR5A
Tchem
Serotonin 5a (5-HT5a) receptor
(1433 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR6
Tchem
Serotonin 6 (5-HT6) receptor
(9749 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
GLA
Tclin
Alpha-galactosidase A
(5444 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
AKT2
Tchem
Serine/threonine-protein kinase AKT2
(4301 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
IKBKB
Tchem
Inhibitor of nuclear factor kappa B kinase beta subunit
(5554 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
AURKB
Tchem
Serine/threonine-protein kinase Aurora-B
(6805 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PIM1
Tchem
Serine/threonine-protein kinase PIM1
(9629 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PKN2
Tchem
Protein kinase N2
(1991 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CSK
Tchem
Tyrosine-protein kinase CSK
(2395 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
RPS6KA5
Tchem
Ribosomal protein S6 kinase alpha 5
(3355 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PRKD1
Tchem
Protein kinase C mu
(1904 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PLK1
Tchem
Serine/threonine-protein kinase PLK1
(28605 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
RPS6KA1
Tchem
Ribosomal protein S6 kinase alpha 1
(2796 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CAMK1
Tchem
CaM kinase I alpha
(1664 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
GAA
Tclin
Lysosomal alpha-glucosidase
(35701 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAPK13
Tchem
MAP kinase p38 delta
(2605 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAPKAPK2
Tchem
MAP kinase-activated protein kinase 2
(4814 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAPKAPK5
Tchem
MAP kinase-activated protein kinase 5
(2831 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ALDH1A1
Tchem
Aldehyde dehydrogenase 1A1
(77053 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ROCK2
Tclin
Rho-associated protein kinase 2
(6206 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CYP2D6
Tclin
Cytochrome P450 2D6
(33882 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAPK9
Tchem
c-Jun N-terminal kinase 2
(4655 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAPK10
Tchem
c-Jun N-terminal kinase 3
(3396 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAP2K1
Tclin
Dual specificity mitogen-activated protein kinase kinase 1
(4127 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CASP1
Tchem
Caspase-1
(6235 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PRKCA
Tchem
Protein kinase C alpha
(5923 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAPK3
Tchem
MAP kinase ERK1
(4725 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CDK2
Tchem
Cyclin-dependent kinase 2
(9050 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
关联靶点（其它种属）
TPR
Trypanothione reductase (189 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Htr7
Serotonin 7 (5-HT7) receptor (19 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ampC
Beta-lactamase AmpC (62480 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Cruzipain (33337 活性数据)
Mapk1
MAP kinase ERK2 (650 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Leishmania infantum (5912 活性数据)
Plasmodium falciparum (966862 活性数据)
Candida albicans (78123 活性数据)
Leishmania amazonensis (3813 活性数据)
Leishmania donovani (89745 活性数据)
CHO (4503 活性数据)
lef
Anthrax lethal factor (7585 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
GCN5
Histone acetyltransferase GCN5 (89 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Dyrk1a
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (1629 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mapt
Microtubule-associated protein tau (6 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Rorc
Nuclear receptor ROR-gamma (89407 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Impa1
Inositol monophosphatase 1 (16203 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
FTL
Ferritin light chain (43324 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
STE24
CAAX prenyl protease 1 (95 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Gabrp
GABA-A receptor; anion channel (5731 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SARS-CoV-2 (38078 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
名称和识别符
| 分子类型 | 小分子 |
|---|---|
| IUPAC Name | 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole |
| INCHI | InChI=1S/C13H14N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7,15H,5-6H2,1-2H3 |
| InChi Key | RERZNCLIYCABFS-UHFFFAOYSA-N |
| Canonical SMILES | CC1=NCCC2=C1NC3=C2C=CC(=C3)OC |
| Isomeric SMILES | CC1=NCCC2=C1NC3=C2C=CC(=C3)OC |
| WGK Germany | 3 |
| RTECS | UU9800000 |
| 关联CAS | 6027-98-1 |
| 分子量 | 214.27 |
| Beilstein号 | 207310 |
| Reaxy-Rn | 207310 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=207310&ln= |
化学和物理性质
| 熔点 | 251°C(lit.) |
|---|---|
| 分子量 | 214.260 g/mol |
| XLogP3 | 2.100 |
| 氢键供体数Hydrogen Bond Donor Count | 1 |
| 氢键受体数Hydrogen Bond Acceptor Count | 2 |
| 可旋转键计数Rotatable Bond Count | 1 |
| 精确质量Exact Mass | 214.111 Da |
| 单同位素质量Monoisotopic Mass | 214.111 Da |
| 拓扑极表面积Topological Polar Surface Area | 37.400 Ų |
| 重原子数Heavy Atom Count | 16 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 302.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
安全和危险性（GHS）
| 象形图 | GHS08 |
|---|---|
| 信号词 | Warning |
| 危险声明 |
H371: 可能会损坏器官 |
| 预防措施声明 |
P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P308+P316: 如果暴露或担心：立即寻求紧急医疗救助。 |
| WGK Germany | 3 |
| RTECS | UU9800000 |
| Reaxy-Rn | 207310 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=207310&ln= |
| Merck Index | 4613 |
| 个人防护装备 | Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter |
技术规格说明书
| Concentration(Compounding value) | 9-11(mmol/L) |
|---|---|
| Record the entire process by video | Conform |
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱: