Influenza virus-IN-1 (compound 14) is a potent influenza A virus inhibitor with an EC 50 of 2.46 µM and CC 50 of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PA N endonuclease with EC 50 of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities.