Blood picture: the vast majority of patients have different degrees of anemia, the severity of anemia with the progress of the disease and aggravation of the anemia is mostly positive cell positive pigmentation, a small number of hypochromic, there are also large-cell people, red blood cells are often presented as a "string of money-like" arrangement. Blood sedimentation is also significantly faster white blood cell count is normal or low, the cause of leukopenia is related to bone marrow damage, white blood cell classification. Lymphocytes are relatively increased, accounting for 40-55%. Myeloma cells can be seen in external blood film, mostly 2%-3%, if the tumor cells exceed 20% absolute value of more than 2 × 109/L, the diagnosis of plasma cell leukemia can be considered. Platelet count is normal or low, and thrombocytopenia is associated with bone marrow infiltration and microthrombosis. This experiment is from Mudanjiang Medical College, undergraduate 5-year laboratory guide for testing majors.

Operation method

Multiple Myeloma Detection Tests

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Blood picture: the vast majority of patients have different degrees of anemia, the severity of anemia with the progress of the disease and aggravation of anemia is mostly positive cell positive pigmentation, a small number of hypochromic, there are also large-cell people, red blood cells are often presented as a "string of money-like" arrangement. Blood sedimentation is also significantly faster white blood cell count is normal or low, the cause of leukopenia is related to bone marrow damage, white blood cell classification. Lymphocytes are relatively increased, accounting for 40-55%. Myeloma cells can be seen in external blood film, mostly 2%-3%, if the tumor cells exceed 20% absolute value of more than 2 × ^109/L, the diagnosis of plasma cell leukemia can be considered. Platelet count is normal or low, and thrombocytopenia is associated with bone marrow infiltration and microthrombosis.

Bone marrow image: Bone marrow aspiration examination is decisive for this disease, the tumor cells of early patients can be focally distributed, so it is necessary to be multi-site, multiple puncture, to help diagnose the tumor cells are often distributed in piles in the tail of the smear. The bone marrow image is generally proliferative and active, and the proportion of each system often varies with the number of tumor cells. When the proportion of tumor cells is high, the granulocytes and erythrocytes are obviously reduced, and the plasma cells in normal bone marrow are l-1.5%, but the abnormal plasma cells increase in multiple myeloma, generally 5-10%. In multiple myeloma, the abnormal plasma cells are increased, usually 5-10%. In many cases, the number of plasma cells can be as high as 70-95%, and the size, morphology and maturity of tumor cells are obviously abnormal.

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