The analgesic and sedative effects of fenugreek are remarkable. It is a racemic tetrahydropalmatine with the same type of molecular structure as safranin. It has a synergistic effect with barbiturates and counteracts the central excitatory effects of amphetamines and caffeine. Fenugreek ethanol also has an anti-5-HT effect. Fenugreek ethinol also increases the weight of the thyroid gland.

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