BioReagent 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
低密度脂蛋白为血清蛋白之一，主要由肝脏合成，与冠心病的发生和动脉粥样硬化损伤呈正相关，是脂类疾病分类和风险预测的一个重要指标。 测定原理：用沉淀剂分离血清中的低密度脂蛋白胆固醇，利用酯酶催化胆固醇酯水解生成游离胆固醇和游离脂肪酸，从而把胆固醇酯转化为FC；进一步利用胆固醇氧化酶催化FC氧化，生成△4-胆甾烯酮和H₂O₂；再利用过氧化物酶催化H₂O₂氧化4-氨基安替比林和酚，生成红色醌类化合物；在500nm有特征吸收峰。
Low-density lipoprotein is one of the serum proteins, primarily synthesized by the liver. It is positively correlated with the occurrence of coronary heart disease and the development of atherosclerotic lesions, serving as a key indicator for the classification of lipid disorders and the prediction of associated risks. Testing Principle: A precipitating agent is used to isolate low-density lipoprotein cholesterol from serum. Cholesterol ester is hydrolyzed into free cholesterol and free fatty acids under the catalysis of esterase, thereby converting cholesterol ester into FC. Subsequently, cholesterol oxidase catalyzes the oxidation of FC to produce △4-cholestenone and H₂O₂. Finally, peroxidase catalyzes the oxidation of 4-aminoantipyrine and phenol by H₂O₂ to generate red quinone compounds, which exhibit a characteristic absorption peak at 500 nm.
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